Assistant, Associate or Full Research Scientist - Head of the Human Liver Cell Isolation Lab
University of California, San Diego
The Department of Medicine (http://med.ucsd.edu) and the Division of Gastroenterology & Hepatology at University of California, San Diego, is committed to academic excellence and diversity within the faculty, staff, and student body and seeks a Research Scientist to be the Head of a Human Liver Cell Isolation Lab.
The selected candidate will perform a) isolation of four cell types (hepatocytes, Hepatic Stellate Cells, Kupffer cells, and Endothelial cells) from livers which are rejected for transplantation; b) cell characterization and cryopreservation, storage, cataloging; c) in vitro studies using cell stimulation, co-culturing; d) generation of humanized mice. The candidate will develop several independent scientific projects focused on NASH and ASH-induced cross-talk between human hepatocytes/HSCs/Kupffer cells, characterization of their gene expression profile and epigenetic signature. The candidate will apply for NIH funds to support the Human Cell Isolation lab and research projects. This position will be supported by one technician full time.
Candidates must have a PhD or equivalent with an emphasis relevant to Gastroenterology.
Candidates with demonstrated experience in whole human liver perfusion and cell isolation using gradient centrifugation, primary murine/human cell isolation techniques, primary cell culture, immunocytochemistry, RNA-Seq, single-cell RNA-Seq, ChIP-Seq, flow cytometry, grant writing, excellent leadership skills are preferred
Appointment will be at the Assistant, Associate or Full Research Scientist rank. Salary is commensurate with qualifications and based on University of California pay scales.
The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to gender, race, color, religion, sex, national origin, disability, age or protected veterans status.
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Statement of Contributions to Diversity - Applicants should summarize their past or potential contributions to diversity. See our Faculty Equity site for more information.